Numerical simulation on pressure field inside liquid column by focused ultrasound

Blood Brain Barrier Disruption by Focused Ultrasound and Microbubbles: A Numerical Study on Mechanical Effects

Introduction: Microbubbles are widely used as contrast agent in diagnostic ultrasound. Recently they have shown good potential for applications in the therapeutic field such as drug delivery to the brain. Recent studies have shown focused ultrasound in conjunction with injected micro-bubbles could temporarily disrupt blood-brain barrier and let therapeutic agents transport into...

Numerical simulation of the nonlinear ultrasonic pressure wave propagation in a cavitating bubbly liquid inside a sonochemical reactor.

We investigate the acoustic wave propagation in bubbly liquid inside a pilot sonochemical reactor which aims to produce antibacterial medical textile fabrics by coating the textile with ZnO or CuO nanoparticles. Computational models on acoustic propagation are developed in order to aid the design procedures. The acoustic pressure wave propagation in the sonoreactor is simulated by solving the H...

Numerical Study for Optimizing Parameters of High-Intensity Focused Ultrasound-Induced Thermal Field during Liver Tumor Ablation: HIFU Simulator

Introduction High intensity focused ultrasound (HIFU) is considered a noninvasive and effective technique for tumor ablation. Frequency and acoustic power are the most effective parameters for temperature distribution and the extent of tissue damage. The aim of this study was to optimize the operating transducer parameters such as frequency and input power in order to acquire suitable temperatu...

State of the Field: Focused Ultrasound Immunomodulation

Numerical Simulation of Granular Column Collapses with Pressure-Dependent Viscoplastic Model using the Smoothed Particle Hydrodynamic Method

This paper presents a numerical analysis of granular column collapse phenomenon using a two-dimensional smoothed particle hydrodynamics model and a local constitutive law proposed by Jop et al. This constitutive law, which is based on the viscoplastic behaviour of dense granular material flows, is characterized by an apparent viscosity depending both on the local strain rate and the local press...